A Clinical Case of Metastatic Colorectal Cancer Associated with a Mutation of the Kras Gene in an Elderly Patient, Taking into Account the Comorbidity Index

In Russia and other developed countries, a colorectal cancer is one of the main causes of deaths from malignant neoplasms. For last ten years a number of patients with colorectal cancer has been growing up each year all around the world. It relates with cancer incidence increase, diagnosis improvement, good treatment results. At the same time, the incidence of colorectal tumors steadily increases with age. Before the start of elderly and senile people anticancer therapy it’s necessary to assess potential risks and ability of positive results achieve. There is a little information in the literature on usage of complex Comprehensive Geriatric Assessment (CGA), Cancerand Aging Research Group (CARG) toxicity assessment for elderly and senile people before the start of specialized antitumor therapy (chemotherapy). In this article the author observed a clinical experience of chemotherapy treatment of elderly patient (76 years old) with metastatic colorectal cancer associated with KRAS gene mutation.