Esomeprazole inhibits liver inflammation and carcinogenesis by suppressing farnesoid X receptors and NF-κB signaling

Our study provides insight into the potential therapeutic effects of esomeprazole on hepatic inflammation and carcinogenesis by inhibiting LPS-induced NF-κB and FXR expression in HepG2 cells.

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Publication Details

Journal
Advances in Clinical and Experimental Medicine
Published
2024-12-04
DOI
https://doi.org/10.17219/acem/191596
Primary Topic
Cytokine Signaling Pathways and Interactions
Type
article
Field-Weighted Citation Impact
0.00
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article

Esomeprazole inhibits liver inflammation and carcinogenesis by suppressing farnesoid X receptors and NF-κB signaling

Yen-Chun Peng, Yi-Wen Hung, Yi‐Chin Yang, Chien-Chang Lu
Advances in Clinical and Experimental Medicine
Cytokine Signaling Pathways and Interactions
article

Esomeprazole inhibits liver inflammation and carcinogenesis by suppressing farnesoid X receptors and NF-κB signaling

Yen-Chun Peng, Yi-Wen Hung, Yi‐Chin Yang, Chien-Chang Lu
article en

Abstract

Our study provides insight into the potential therapeutic effects of esomeprazole on hepatic inflammation and carcinogenesis by inhibiting LPS-induced NF-κB and FXR expression in HepG2 cells.

Advances in Clinical and Experimental MedicineVol. 34(7)
National Yang Ming Chiao Tung University (TW), National Chung Hsing University (TW), China Medical University (TW), Taichung Veterans General Hospital (TW), China Medical University Hospital (TW)
Good health and well-being
Openalex Percentile: Top 62%
Cytokine Signaling Pathways and Interactions
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