Oral Health, Inflammation, and Cardiometabolic Factors in the VA Million Veteran Program
This study of veterans underscores the important cardiometabolic links of self-reported poor OH and tooth loss, akin to those observed with periodontitis, even after adjusting for potential confounders related to demographics, lifestyle, and inflammation.Knowledge Transfer Statement:Exploring cardiometabolic associations with self-reported OH, clinically diagnosed periodontitis, and tooth loss using the ICD in the Veterans Affairs Million Veteran Program, we found significant associations. These associations persisted after adjustment for inflammatory confounders. These findings emphasized the benefit of assessing OH as a vital indicator of overall cardiometabolic health in large-scale biobank studies.
Authors
- Themistocles L. Assimes (ORCID: https://orcid.org/0000-0003-2349-0009)
- Yau‐Hua Yu (ORCID: https://orcid.org/0000-0002-4723-5064)
- Kyong‐Mi Chang (ORCID: https://orcid.org/0000-0001-6811-9364)
- Kathryn M. Pridgen
- Julie Ann Lynch (ORCID: https://orcid.org/0000-0003-0108-2127)
- Philip S. Tsao (ORCID: https://orcid.org/0000-0001-7274-9318)
- Tyler J. Nelson (ORCID: https://orcid.org/0000-0001-5216-7337)
- Donald R. Miller (ORCID: https://orcid.org/0000-0002-7881-8801)
- Christopher J. O’Donnell (ORCID: https://orcid.org/0000-0002-2667-8624)
- John M. Wells
Institutions
- Tufts University (US)
- University of Massachusetts Lowell (US)
- Harvard University (US)
- VA Palo Alto Health Care System (US)
- University of Utah (US)
- VA Boston Healthcare System (US)
- VA Salt Lake City Healthcare System (US)
- VA New England Healthcare System (US)
- VA San Diego Healthcare System (US)
- Philadelphia VA Medical Center (US)
- University of Pennsylvania (US)
- Stanford University (US)
Publication Details
- Journal
- JDR Clinical & Translational Research
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1177/23800844241291780
- Citations
- 2
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- Office of Research and Development
- National Institute of Dental and Craniofacial Research