Влияние чрескожного коронарного вмешательства на функцию почек у больных ИБС

To investigate the impact of PCI on renal function in IHD patients and identify risk factors for CIN development. Background. Contrast-induced nephropathy (CIN) is a common complication among patients with ischemic heart disease (IHD) undergoing percutaneous coronary intervention (PCI). Understanding the pathogenesis, risk factors, and preventive measures of CIN is essential for reducing morbidity and mortality. Materials and methods. An analysis was conducted on patients with IHD who underwent PCI with contrast media administration. Renal function indicators, including serum creatinine levels and glomerular filtration rate, were assessed pre- and post-procedure. Clinical manifestations, CIN incidence, and associated risk factors were evaluated. Results.The incidence of CIN varied based on baseline renal function and comorbidities. Key risk factors included elevated baseline serum creatinine, diabetes mellitus, and advanced age. Hydration therapy was effective in reducing the incidence of nephropathy. Conclusion. PCI increases the risk of CIN in IHD patients, particularly in those with predisposing risk factors. Comprehensive renal function assessment and preventive measures are recommended prior to the procedure to minimize risk.

Authors

Publication Details

Journal
Cardiology of Uzbekistan.
Published
2024-10-09
DOI
https://doi.org/10.70626/3060-4850-2024-1-1-20-27
Primary Topic
Acute Kidney Injury Research
Type
article
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article

Влияние чрескожного коронарного вмешательства на функцию почек у больных ИБС

Lola Daminova, Ш Муминов, Б Нигмонов
Cardiology of Uzbekistan.
Acute Kidney Injury Research
article

Влияние чрескожного коронарного вмешательства на функцию почек у больных ИБС

Lola Daminova, Ш Муминов, Б Нигмонов
article en

Abstract

To investigate the impact of PCI on renal function in IHD patients and identify risk factors for CIN development. Background. Contrast-induced nephropathy (CIN) is a common complication among patients with ischemic heart disease (IHD) undergoing percutaneous coronary intervention (PCI). Understanding the pathogenesis, risk factors, and preventive measures of CIN is essential for reducing morbidity and mortality. Materials and methods. An analysis was conducted on patients with IHD who underwent PCI with contrast media administration. Renal function indicators, including serum creatinine levels and glomerular filtration rate, were assessed pre- and post-procedure. Clinical manifestations, CIN incidence, and associated risk factors were evaluated. Results.The incidence of CIN varied based on baseline renal function and comorbidities. Key risk factors included elevated baseline serum creatinine, diabetes mellitus, and advanced age. Hydration therapy was effective in reducing the incidence of nephropathy. Conclusion. PCI increases the risk of CIN in IHD patients, particularly in those with predisposing risk factors. Comprehensive renal function assessment and preventive measures are recommended prior to the procedure to minimize risk.

Cardiology of Uzbekistan.Vol. 1(1)
Good health and well-being
Openalex Percentile: Top 69%
Acute Kidney Injury Research
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