Geraniol Ameliorates Pentylenetetrazol-Induced Epilepsy, Neuroinflammation, and Oxidative Stress via Modulating the GABAergic Tract: In vitro and in vivo studies

Ger reduced the oxidative stress status, neuroinflammation and apoptosis and activated GABAergic neurotransmission, which might clarify its anticonvulsant. Ger protects animals against PTZ prompted kindling as established by the enhancement in short term as well as long-term memory. Ger mitigated the injury induced by Glu in NGF prompted PC12 cell.

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Publication Details

Journal
Drug Design Development and Therapy
Published
2024-12-01
DOI
https://doi.org/10.2147/dddt.s481985
Citations
8
Primary Topic
Medicinal Plants and Neuroprotection
Type
article
Field-Weighted Citation Impact
5.73
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article

Geraniol Ameliorates Pentylenetetrazol-Induced Epilepsy, Neuroinflammation, and Oxidative Stress via Modulating the GABAergic Tract: In vitro and in vivo studies

Maged E. Mohamed, Mervt M. Almostafa, Nancy S. Younis
8 citations
Drug Design Development and Therapy
Medicinal Plants and Neuroprotection
5.73
article

Geraniol Ameliorates Pentylenetetrazol-Induced Epilepsy, Neuroinflammation, and Oxidative Stress via Modulating the GABAergic Tract: In vitro and in vivo studies

Maged E. Mohamed, Mervt M. Almostafa, Nancy S. Younis
article en
8 citations

Abstract

Ger reduced the oxidative stress status, neuroinflammation and apoptosis and activated GABAergic neurotransmission, which might clarify its anticonvulsant. Ger protects animals against PTZ prompted kindling as established by the enhancement in short term as well as long-term memory. Ger mitigated the injury induced by Glu in NGF prompted PC12 cell.

Drug Design Development and TherapyVol. Volume 18
Zagazig University (EG), King Faisal University (SA)
Openalex Percentile: Top 4%
Medicinal Plants and Neuroprotection
5.73
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