Adhesive, Biocompatible, Antibacterial, and Degradable Collagen-Based Conductive Hydrogel as Strain Sensor for Human Motion Monitoring

The conductive hydrogels (CHs) are promising for developing flexible energy storage devices, flexible sensors, and electronic skin due to the unique features of excellent flexibility and high conductivity. However, poor biocompatibility and antibacterial properties seriously limit their application in the biomedical field. Collagen, one of the main components of the extracellular Matrix (ECM), is the ideal matrix for constructing hydrogels due to good biocompatibility with human tissue. Here, dopamine-polypyrrole-collagen (DA-PPY-COL) hydrogel was constructed by dopamine-mediated pyrrole in situ polymerization in a collagen matrix. As a strain sensor, it can be affixed to different parts of the human body to monitor large-scale motion movements and fine micro-expressions in real time. The performance was attributed to its good self-adhesion, flexibility, and electrical conductivity. Biological experiments have shown that it has good antimicrobial properties, biocompatibility, and degradability, allowing the hydrogel to safely monitor human motor behavior. This work not only offers a material preparation strategy for constructing biomimetic electronic skin and wearable sensors but also demonstrates the great potential prospect for implantable degradable medical device applications.