Revisiting the follicle-stimulation hormone receptor expression and function in human myometrium and adipose tissue
These findings suggest that the FSHR signaling pathway does not regulate myometrial contractility during pregnancy. Additionally, the absence of FSHR expression in both VAT and SCAT implied that FSHR does not play a role in the functional signaling pathways in adipose tissues. In conclusion, our findings contradict earlier data on the involvement of FSH-FSHR signaling in regulating myometrial contractility near term, as well as in adipose tissue function.
Authors
- M Kulikowski
- Tomasz Kleszczewski (ORCID: https://orcid.org/0000-0002-0250-8698)
- Paweł Gołaszewski
- Maria Sztachelska (ORCID: https://orcid.org/0000-0003-0544-3436)
- Piotr Bernaczyk (ORCID: https://orcid.org/0000-0003-3401-6599)
- Sławomir Wołczyński (ORCID: https://orcid.org/0000-0002-7806-1394)
- Kamila Puławska (ORCID: https://orcid.org/0000-0002-9179-0444)
- Nafis A. Rahman (ORCID: https://orcid.org/0000-0001-5257-870X)
- Gabriela Milewska (ORCID: https://orcid.org/0000-0001-9008-8285)
- Beata Modzelewska (ORCID: https://orcid.org/0000-0002-1051-7906)
- Ewelina Palak (ORCID: https://orcid.org/0000-0002-6485-8394)
- Adam Lemancewicz
- Donata Ponikwicka‐Tyszko (ORCID: https://orcid.org/0000-0003-1086-7460)
- Ilpo Huhtaniemi (ORCID: https://orcid.org/0000-0001-9092-7886)
- Hady Razak Hady
- Aleksandra N. Lupinska
- Maria L. Koivukoski
Institutions
- Medical University of Białystok (PL)
- University of Turku (FI)
- InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences (PL)
- Imperial College London (GB)
- Polish Academy of Sciences (PL)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1186/s10020-024-01015-2
- Citations
- 1
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.33
Funders
- European Commission
- Opetushallitus