Coordination-Assisted Ni-Catalyzed Regio- and Enantioselective 1,2-Borylalkylation of Unactivated Alkenes
Herein we successfully utilize various directing groups to achieve a ligand-enabled nickel-catalyzed 1,2-borylalkylation of unactivated alkenes. A β-amino alcohol was employed as the ligand for non-asymmetric 1,2-borylalkylation of unactivated alkenes, while a bulky chiral diamine ligand was used to achieve the asymmetric 1,2-borylalkylation of allyl amides.
Authors
- Guodong Ju (ORCID: https://orcid.org/0000-0001-7593-8077)
- Yuqin Zhu
- Jia‐Xin Wang (ORCID: https://orcid.org/0000-0001-8296-8696)
- Chao Wang (ORCID: https://orcid.org/0000-0001-6979-8506)
- Wenyi Li (ORCID: https://orcid.org/0000-0003-3584-0301)
- Zhetai Feng
Institutions
- Hengyang Normal University (CN)
- Tianjin Normal University (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1021/acs.orglett.4c03791
- Citations
- 6
- Primary Topic
- Organoboron and organosilicon chemistry
- Type
- article
- Field-Weighted Citation Impact
- 1.50
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Tianjin City
- Tianjin Normal University