Development of BCMA-Targeted Bispecific Natural Killer Cell Engagers for Multiple Myeloma Treatment
Our results indicate that the format design of NKCEs influences their functionalities, underscoring the importance of format selection in optimizing NKCE-based therapies for MM. This study provides valuable insights for developing next-generation NKCEs and advancing therapeutic strategies for MM and potentially other malignancies.
Authors
- Yuansheng Yang (ORCID: https://orcid.org/0000-0002-0026-7069)
- Shiyi Goh Fang
- Shengli Xu (ORCID: https://orcid.org/0000-0002-2541-3608)
- Minchuan Zhang
- Kong‐Peng Lam (ORCID: https://orcid.org/0000-0002-1316-4333)
- Han Ping Loh (ORCID: https://orcid.org/0000-0003-1972-0190)
Institutions
- Agency for Science, Technology and Research (SG)
- National University of Singapore (SG)
- Nanyang Technological University (SG)
- Singapore Immunology Network (SG)
- Bioprocessing Technology Institute (SG)
Publication Details
- Journal
- Antibodies
- Published
- 2024-11-29
- DOI
- https://doi.org/10.3390/antib13040097
- Citations
- 1
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.45
Funders
- National Research Foundation