The role of H3K27 acetylation in oxygen-glucose deprivation-induced spinal cord injury and potential for neuroprotective therapies
Our data underscore the pivotal role of H3K27ac in the organotypic spinal cord slice culture model following OGD exposure, offering promising avenues for neuroprotective therapies via epigenetic-immune regulation.
Authors
- Heying Wang (ORCID: https://orcid.org/0000-0003-3479-7487)
- Jingjie Liu
- Jing Wang (ORCID: https://orcid.org/0000-0002-7959-0685)
- Weina Li (ORCID: https://orcid.org/0000-0002-8728-3167)
- Ting Zhou (ORCID: https://orcid.org/0009-0003-8502-3219)
- Zheng Guan (ORCID: https://orcid.org/0000-0001-8617-8114)
- Yu Gong (ORCID: https://orcid.org/0000-0003-1467-4711)
Institutions
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1016/j.brainresbull.2024.111152
- Primary Topic
- Histone Deacetylase Inhibitors Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China