Efficient development of high drug loaded posaconazole tablets enabled by amorphous solid dispersion
A 50% API-loaded posaconazole tablet was developed in 14 days using just 1.5 g of API through systematic evaluation of stability, dissolution, and manufacturability.
Authors
- Changquan Calvin Sun (ORCID: https://orcid.org/0000-0001-7284-5334)
- Sichen Song (ORCID: https://orcid.org/0000-0002-4302-0314)
- Ronald A. Siegel (ORCID: https://orcid.org/0000-0002-9591-1282)
- Tianyi Xiang (ORCID: https://orcid.org/0009-0001-9052-1517)
Institutions
- University of Minnesota (US)
Publication Details
- Journal
- RSC Pharmaceutics
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1039/d4pm00301b
- Citations
- 5
- Primary Topic
- Drug Solubulity and Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 1.04
Funders
- National Science Foundation