The impact of positive surgical margins after cystectomy on oncological outcomes: a nationwide study
Positive margins should be considered a 'high risk feature', as they result in increased risk of disease progression and impaired survival outcomes. These findings support further investigation of the potential efficacy of adjuvant therapy (i.e., radiotherapy and systemic therapy) among patients with positive surgical margins.
Authors
- Katja K.H. Aben (ORCID: https://orcid.org/0000-0002-0214-2147)
- Niven Mehra (ORCID: https://orcid.org/0000-0002-4794-1831)
- Richard P. Meijer (ORCID: https://orcid.org/0000-0003-2510-7982)
- Antoine G. van der Heijden (ORCID: https://orcid.org/0000-0002-8839-8601)
- J.A. Witjes
- Anke Richters (ORCID: https://orcid.org/0000-0002-1580-1543)
- Tri Q. Nguyen (ORCID: https://orcid.org/0000-0001-6475-0706)
- Joost L. Boormans
- Lambertus A Kiemeney
- J. Bosveld
Institutions
- Radboud University Nijmegen (NL)
- Radboud University Medical Center (NL)
- University Medical Center Utrecht (NL)
- Netherlands Comprehensive Cancer Organisation (NL)
- Erasmus MC Cancer Institute (NL)
Publication Details
- Journal
- British Journal of Urology
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1111/bju.16611
- Citations
- 2
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- AstraZeneca
- Merck
- Gilead Sciences
- KWF Kankerbestrijding
- Astellas Pharma