Investigation of the correlation between AGRN expression and perineural invasion in colon cancer
We found that AGRN is significantly overexpressed in colon cancer tissues exhibiting PNI and is linked to poor patient survival. AGRN and its related genes may contribute to PNI by promoting tumor cell invasion and neural cell growth. Hence, AGRN may play a crucial role in the initiation and progression of PNI in colon cancer.
Authors
- Kaiyue Gao
- Haijia Zhang
- Fanqi Meng (ORCID: https://orcid.org/0000-0001-9921-089X)
- Lei Chen (ORCID: https://orcid.org/0009-0003-4906-5163)
- Lijie Wang (ORCID: https://orcid.org/0000-0001-8267-0048)
- Jiannan Li (ORCID: https://orcid.org/0000-0001-8409-4910)
- Funing Yang (ORCID: https://orcid.org/0000-0002-4513-1309)
- Jiandong Tai
Institutions
- Jilin University (CN)
- First Hospital of Jilin University (CN)
- Second Affiliated Hospital of Jilin University (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2024-12-03
- DOI
- https://doi.org/10.3389/fmolb.2024.1510478
- Primary Topic
- Cancer Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00