Daidzein Inhibits Non-small Cell Lung Cancer Growth by Pyroptosis
In summary, this study demonstrated that daidzein inhibits NSCLC growth by inducing pyroptosis. Key pathway modulators ASC, CASP1, and IL-1β were identified as primary targets of daidzein. These findings offer insights into the molecular mechanisms underlying the anti-NSCLC effects of daidzein and could offer dietary recommendations for managing NSCLC.
Authors
- Fanfan Zeng (ORCID: https://orcid.org/0000-0002-4731-7641)
- Denggang Fu (ORCID: https://orcid.org/0000-0001-7274-033X)
- Yu Zhang (ORCID: https://orcid.org/0000-0002-3217-0245)
- Xin Wang (ORCID: https://orcid.org/0000-0001-8891-1447)
- Ting Luo (ORCID: https://orcid.org/0009-0005-2271-8202)
- Chengman Wang
Institutions
- Jiujiang University (CN)
- Nanchang University (CN)
- Medical University of South Carolina (US)
- First Affiliated Hospital of Jiangxi Medical College (CN)
Publication Details
- Journal
- Current Pharmaceutical Design
- Published
- 2024-12-03
- DOI
- https://doi.org/10.2174/0113816128330530240918073721
- Citations
- 5
- Primary Topic
- Phytoestrogen effects and research
- Type
- article
- Field-Weighted Citation Impact
- 2.12