EXAMINING THE ROLE OF SUPAR AND HS-CRP LEVELS IN PREDICTING CORONARY ARTERY DISEASE SEVERITY IN ACUTE MYOCARDIAL INFARCTION: AN AGE-STRATIFIED ANALYSIS INCORPORATING SYNTAX SCORE
ABSTRACT Objective: This study examines the association between traditional inflammatory biomarkers, suPAR levels in elderly and young myocardial infarction patients, and coronary artery disease severity. Materials and Methods: In this study, 332 participants, including 227 acute myocardial infarction (AMI) patients and 107 controls, underwent evaluation through Syntax Score analysis, suPAR, and hs-CRP level assessments. AMI patients were divided into young and elderly groups based on age. Syntax Score was utilized to ascertain the severity of coronary artery disease. Results: suPAR plasma concentrations were significantly higher in AMI patients compared to controls, with values of 2.76 (2.32-3.56) in the young MI group and 3.33 (2.43-4.41) in the elderly MI group, versus 2.33 (1.94-3.11) in the control group (p
Authors
- Abdullah Tunçez (ORCID: https://orcid.org/0000-0002-6512-1327)
- Hüseyin Tezcan
- Muhammed Ulvi Yalçın (ORCID: https://orcid.org/0000-0003-3750-8011)
- Kenan Demır (ORCID: https://orcid.org/0000-0003-0037-0549)
- Bülent Behlül Altunkeser (ORCID: https://orcid.org/0000-0003-0456-3356)
- Onur Can Polat (ORCID: https://orcid.org/0000-0002-1366-6675)
- Nazif Aygül (ORCID: https://orcid.org/0000-0002-0424-231X)
- Bahadır Öztürk (ORCID: https://orcid.org/0000-0003-2654-7621)
- Aslıhan Merve Toprak (ORCID: https://orcid.org/0000-0002-7096-9146)
- Muhammet Salih Ateş (ORCID: https://orcid.org/0000-0003-4099-0064)
Institutions
- Selçuk University (TR)
- Ahi Evran University (TR)
- State Hospital (GB)
- City Hospital (GB)
- Konya Eğitim ve Araştırma Hastanesi (TR)
- Kayseri Eğitim ve Araştırma Hastanesi (TR)
- Rize Devlet Hastanesi (TR)
- Serik Devlet Hastanesi
Publication Details
- Journal
- Meandros Medical And Dental Journal
- Published
- 2024-12-03
- DOI
- https://doi.org/10.69601/meandrosmdj.1531084
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Selçuk Üniversitesi