Atg5-deficient mesenchymal stem cells protect against non-alcoholic fatty liver by accelerating hepatocyte growth factor secretion
Our research findings suggest that Atg5-deficient MSCs protect against NAFLD by accelerating HGF secretion. This indicates that Atg5 gene-modified MSCs may represent a promising strategy for treating NAFLD.
Authors
- Xue-Fang Du
- Tingmin Chang
- YG Song
- Caifeng Zhang
- Ké Li (ORCID: https://orcid.org/0000-0003-4869-5393)
- Yanan Jiang (ORCID: https://orcid.org/0000-0001-6129-643X)
- Lanfang Zhang (ORCID: https://orcid.org/0000-0003-3159-9004)
- Yuyu Wang (ORCID: https://orcid.org/0000-0002-5380-9095)
- Juanjuan Ji
Institutions
- Zhengzhou University (CN)
- First Affiliated Hospital of Xinxiang Medical University (CN)
- Henan Medical University (CN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2024-12-03
- DOI
- https://doi.org/10.1186/s12964-024-01950-x
- Citations
- 4
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.14