Network Pharmacology and In Vivo Experimental Verification of the Mechanism of the Qing'e Pill for Treating Intervertebral Disc Degeneration
The QEP alleviated IDD by modulating the Wnt/MAPK/MMP signaling pathways and reducing the release and activation of key factors.
Authors
- Ruizhe Wu
- Jingqi Zeng (ORCID: https://orcid.org/0000-0003-3210-7315)
- Haoran Xu (ORCID: https://orcid.org/0009-0005-2477-5737)
- Weixing Chen (ORCID: https://orcid.org/0000-0002-5850-1954)
- Fan Wang (ORCID: https://orcid.org/0000-0002-4906-190X)
- Linghui Li (ORCID: https://orcid.org/0000-0002-1371-1317)
- Hui Jin (ORCID: https://orcid.org/0000-0003-0297-3052)
- Huaiyu Ma
- Jie Wu (ORCID: https://orcid.org/0009-0001-1260-4202)
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Wangjing Hospital of China Academy of Chinese Medical Sciences (CN)
- Second Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Current Computer - Aided Drug Design
- Published
- 2024-12-03
- DOI
- https://doi.org/10.2174/0115734099356426241119051916
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00