A new perspective on macrophage-targeted drug research: the potential of KDELR2 in bladder cancer immunotherapy
The findings suggested that patients with high <i>KDELR2</i> expression might benefit from immune checkpoint therapy. <i>KDELR2</i> was also shown to enhance bladder cancer cell proliferation, invasion, and migration, highlighting it as a promising target for macrophage-focused drug development.
Authors
- Zhiyi Zhao (ORCID: https://orcid.org/0000-0002-0777-0687)
- Lingyun Liu (ORCID: https://orcid.org/0000-0002-6755-1259)
- Hongling Jia (ORCID: https://orcid.org/0000-0002-6383-9298)
- Yumeng Li (ORCID: https://orcid.org/0000-0002-1073-4257)
- Zhou Sun (ORCID: https://orcid.org/0009-0000-2428-9679)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Jilin University (CN)
- First Hospital of Jilin University (CN)
- Union Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-12-03
- DOI
- https://doi.org/10.3389/fimmu.2024.1485109
- Citations
- 3
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.72