Identification of SPP1+ macrophages as an immune suppressor in hepatocellular carcinoma using single-cell and bulk transcriptomics
This study underpins the potential of SPP1 as a translational target in immunotherapy for HCC.
Authors
- Adil Mardinoğlu (ORCID: https://orcid.org/0000-0002-4254-6090)
- Hasan Türkez (ORCID: https://orcid.org/0000-0002-7046-8990)
- Han Jin
- Mathias Uhlén (ORCID: https://orcid.org/0000-0002-4858-8056)
- Cheng Zhang (ORCID: https://orcid.org/0000-0002-3721-8586)
- Meng Yuan (ORCID: https://orcid.org/0000-0002-9248-3294)
- Mengnan Shi (ORCID: https://orcid.org/0000-0001-8643-5846)
- Xiangyu Li (ORCID: https://orcid.org/0000-0003-4650-5517)
- Mengzhen Li (ORCID: https://orcid.org/0009-0002-9775-2032)
- Hong Yang (ORCID: https://orcid.org/0000-0001-7126-3076)
- Woonghee Kim
Institutions
- King's College London (GB)
- Science for Life Laboratory (SE)
- Tianjin Medical University General Hospital (CN)
- Atatürk University (TR)
- KTH Royal Institute of Technology (SE)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-12-03
- DOI
- https://doi.org/10.3389/fimmu.2024.1446453
- Citations
- 7
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.68