The efficacy of a nitric oxide-releasing formulation on nares isolated Methicillin-Resistant Staphylococcus aureus in porcine wound infection model
Overall, the positive control Mupirocin 2% was the most effective in eliminating MRSA BAA1686 throughout the study. This experiment demonstrated a downward trend from the highest concentration of NO topical ointment formulations to the lowest concentrations on both assessment days (0.3% - 1.8%). Out of all NO topical ointments, the highest concentration (1.8%) was the most effective with the potential to be an alternative treatment against a MRSA nasal strain biofilm.
Authors
- Joel Gil (ORCID: https://orcid.org/0000-0001-8304-6722)
- Stephen C. Davis (ORCID: https://orcid.org/0000-0002-7075-7426)
- Michael Solis
- Ryan Strong
Institutions
- University of Miami (US)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2024-12-03
- DOI
- https://doi.org/10.3389/fcimb.2024.1501360
- Primary Topic
- Laser Applications in Dentistry and Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health