Urinary microbiome profiling as a non-invasive tool for identifying biomarkers in systemic lupus erythematosus and lupus nephritis
Our study is the first to reveal dysbiosis in the urinary microbiome of patients with SLE. Certain bacterial taxa in the urinary microbiome were identified as potential diagnostic biomarkers for SLE. Furthermore, the functional implications of these bacterial communities suggest their involvement in immune modulation, highlighting the potential for further investigation into their roles in SLE pathogenesis and diagnosis.
Authors
- Ping Yang (ORCID: https://orcid.org/0000-0003-3495-856X)
- Jianmin Gong (ORCID: https://orcid.org/0000-0002-9141-6241)
- Qian Xiang (ORCID: https://orcid.org/0000-0002-8245-2611)
- Adeel Khan (ORCID: https://orcid.org/0000-0001-8766-0551)
- Fei Chen (ORCID: https://orcid.org/0000-0002-7600-1945)
- Zhipeng Xu (ORCID: https://orcid.org/0000-0002-8853-5303)
- Bo Shi (ORCID: https://orcid.org/0000-0003-4661-2259)
Institutions
- Yangtze University (CN)
- Nanjing Drum Tower Hospital (CN)
- Jiangsu Province Hospital (CN)
- University of Science and Technology Bannu (PK)
- Nanjing Jiangning Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2024-12-03
- DOI
- https://doi.org/10.3389/fcimb.2024.1364333
- Citations
- 3
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 1.41
Funders
- National Natural Science Foundation of China
- Nanjing Drum Tower Hospital