Genetic insights into the effect of trace elements on cardiovascular diseases: multi-omics Mendelian randomization combined with linkage disequilibrium score regression analysis
This study uncovered the true causal relationship between trace elements and cardiovascular disease risk using genetic methods, and revealed the significant mediating role of specific plasma proteins and metabolites in this relationship.
Authors
- Chuqiao Wang (ORCID: https://orcid.org/0009-0000-2632-5899)
- Bohang Chen
- Wenjie Li (ORCID: https://orcid.org/0000-0002-1768-1178)
Institutions
- Liaoning University of Traditional Chinese Medicine (CN)
- Affiliated Hospital of Liaoning University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-12-03
- DOI
- https://doi.org/10.3389/fimmu.2024.1459465
- Citations
- 1
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.47