Degradation Pattern of a Biodegradable and Photocurable Sealants Based on Hyaluronic Acid : A Serial Magnetic Resonance Imaging Observational Study in Rat Craniectomy Model
HA photosealant showed gradual degradation in vivo while maintaining mechanical strength until the dura was repaired for preventing CSF leakage without inflammation and toxicity. HA photosealant has great potentials for clinical application for dural repair with biodegradable properties and biocompatibility.
Authors
- Sijoon Lee (ORCID: https://orcid.org/0000-0002-5870-687X)
- Seung Yun Yang (ORCID: https://orcid.org/0000-0002-1233-8960)
- Dong Hwan Kim (ORCID: https://orcid.org/0000-0002-4345-8308)
- Hyeseon Lee (ORCID: https://orcid.org/0000-0003-0975-686X)
- Kyoung Hyup Nam
- Mahnjeong Ha
Institutions
- Busan Digital University (KR)
- Pusan National University Hospital (KR)
- Daegu-Gyeongbuk Medical Innovation Foundation (KR)
- Pusan National University (KR)
Publication Details
- Journal
- Journal of Korean Neurosurgical Society
- Published
- 2024-12-03
- DOI
- https://doi.org/10.3340/jkns.2024.0138
- Citations
- 2
- Primary Topic
- Collagen: Extraction and Characterization
- Type
- article
- Field-Weighted Citation Impact
- 0.35
Funders
- Pusan National University
- Pusan National University Hospital