Mitochondrial Metabolism as a Potential Novel Therapeutic Target for Lung Adenocarcinoma
High expression of OXPHOS-related genes and PPAR-γ is a poor prognostic factor in LUAD. The levels of OXPHOS vary among cases and within different areas of the tumor. Targeting OXPHOS metabolism may represent a novel therapeutic approach for treating LUAD.
Authors
- Morihito Okada (ORCID: https://orcid.org/0000-0001-7068-6608)
- Kei Kushitani
- Takahiro Mimae (ORCID: https://orcid.org/0000-0001-9993-8928)
- Norifumi Tsubokawa (ORCID: https://orcid.org/0000-0003-1966-1709)
- Yoshihiro Miyata (ORCID: https://orcid.org/0000-0002-4598-1231)
- Makoto Fujiwara (ORCID: https://orcid.org/0000-0002-6799-9774)
- Yukio Takeshima
Institutions
- Hiroshima University (JP)
- Hiroshima University Hospital (JP)
Publication Details
- Journal
- Anticancer Research
- Published
- 2024-12-01
- DOI
- https://doi.org/10.21873/anticanres.17352
- Citations
- 1
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.29