Effects of Curcumin and Its Analogue Desmethoxycurcumin on miR-133b and Its Target Gene GSTP-1 in Cisplatin-resistant Ovarian Cancer Cells

This study demonstrated the potential of CUR and DMC to enhance the efficacy of cisplatin in ovarian cancer treatment. The observed decrease in GSTP-1 and miR-133b expression in cisplatin-resistant cells suggests their involvement in drug resistance and highlights their potential as therapeutic targets.

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Publication Details

Journal
Anticancer Research
Published
2024-12-01
DOI
https://doi.org/10.21873/anticanres.17362
Citations
4
Primary Topic
Curcumin's Biomedical Applications
Type
article
Field-Weighted Citation Impact
0.68
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article

Effects of Curcumin and Its Analogue Desmethoxycurcumin on miR-133b and Its Target Gene GSTP-1 in Cisplatin-resistant Ovarian Cancer Cells

Esin Aktaş Çetin, Özlem Timirci‐Kahraman, Deryanaz Billur, Turgay İşbir et al.
4 citations
Anticancer Research
Curcumin's Biomedical Applications
0.68
article

Effects of Curcumin and Its Analogue Desmethoxycurcumin on miR-133b and Its Target Gene GSTP-1 in Cisplatin-resistant Ovarian Cancer Cells

Esin Aktaş Çetin, Özlem Timirci‐Kahraman, Deryanaz Billur, Turgay İşbir, Esin Bayralı Ülker, Mehmet Fatih Seyhan
article en
4 citations

Abstract

This study demonstrated the potential of CUR and DMC to enhance the efficacy of cisplatin in ovarian cancer treatment. The observed decrease in GSTP-1 and miR-133b expression in cisplatin-resistant cells suggests their involvement in drug resistance and highlights their potential as therapeutic targets.

Anticancer ResearchVol. 44(12)
Yeditepe University (TR), Istanbul Yeni Yüzyıl University (TR), Istanbul University (TR)
Good health and well-being
Openalex Percentile: Top 34%
Curcumin's Biomedical Applications
0.68
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