Ivermectin Enhances Paclitaxel Efficacy by Overcoming Resistance Through Modulation of<i>ABCB1</i>in Non-small Cell Lung Cancer
Combined treatment of PTX-resistant A549 cells with ivermectin and PTX may circumvent PTX resistance caused by P-gp induction, highlighting a novel therapeutic avenue for drug repurposing.
Authors
- Masaru Matsumoto (ORCID: https://orcid.org/0000-0003-0246-395X)
- Anna Hayashi
- Takehiro Tozuka (ORCID: https://orcid.org/0000-0002-3774-8915)
- Mariko Hirao
- Keisuke Yoshida (ORCID: https://orcid.org/0000-0003-4903-7608)
- Kazuo Kasahara (ORCID: https://orcid.org/0000-0001-5551-1543)
- Kakeru Hisakane (ORCID: https://orcid.org/0000-0002-9108-2050)
- Koichiro Kamio (ORCID: https://orcid.org/0000-0002-6870-9548)
- Kazufumi Honda (ORCID: https://orcid.org/0000-0003-1321-5345)
- Takanori Amano (ORCID: https://orcid.org/0000-0002-0213-4745)
- Aya Fukuizumi
- Kuniko Matsuda
- Masahiro Seike (ORCID: https://orcid.org/0000-0002-1572-5472)
- Akihiko Miyanaga (ORCID: https://orcid.org/0000-0003-2026-9181)
- Susumu Takeuchi (ORCID: https://orcid.org/0000-0002-0617-0962)
- Miwako Omori (ORCID: https://orcid.org/0000-0001-7342-2026)
- Rintaro Noro (ORCID: https://orcid.org/0000-0003-4912-4138)
Institutions
- RIKEN BioResource Research Center (JP)
- Nippon Medical School (JP)
Publication Details
- Journal
- Anticancer Research
- Published
- 2024-12-01
- DOI
- https://doi.org/10.21873/anticanres.17355
- Citations
- 1
- Primary Topic
- Helminth infection and control
- Type
- article
- Field-Weighted Citation Impact
- 0.64