Case Report: Surgical Decompression With Subsequent Selumetinib Treatment Leads to Drastic Clinical Improvement in a Patient With a Large Spinal Plexiform Neurofibroma

A combination of decompression surgery and selumetinib therapy provides a promising option for the management of spinal plexiform neurofibromas causing severe neurological deficits.

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Publication Details

Journal
Anticancer Research
Published
2024-12-01
DOI
https://doi.org/10.21873/anticanres.17385
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
Field-Weighted Citation Impact
0.00
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article

Case Report: Surgical Decompression With Subsequent Selumetinib Treatment Leads to Drastic Clinical Improvement in a Patient With a Large Spinal Plexiform Neurofibroma

Lan Kluwe, Catena Kresbach, Lennart Well, Said Farschtschi et al.
Anticancer Research
Neurofibromatosis and Schwannoma Cases
article

Case Report: Surgical Decompression With Subsequent Selumetinib Treatment Leads to Drastic Clinical Improvement in a Patient With a Large Spinal Plexiform Neurofibroma

Lan Kluwe, Catena Kresbach, Lennart Well, Said Farschtschi, Reinhard E. Friedrich, Florian Brembach, Malte Mohme, Thomas Härtung
article en

Abstract

A combination of decompression surgery and selumetinib therapy provides a promising option for the management of spinal plexiform neurofibromas causing severe neurological deficits.

Anticancer ResearchVol. 44(12)
Universität Hamburg (DE), University Medical Center Hamburg-Eppendorf (DE)
Good health and well-being
Openalex Percentile: Top 66%
Neurofibromatosis and Schwannoma Cases
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