Visible light-induced PPh<sub>3</sub>/MI-promoted δ-C(sp<sup>3</sup>)–H chlorination and cyclization with <i>N</i>-chloro-arylsulfonamides <i>via</i> EDA complexes
Triphenylphosphine, iodide and <i>N</i>-chloro-arylsulfonamides could generate amidyl radicals <i>via</i> EDA (Electron Donor-Acceptor) complexes under visible light irradiation, and this strategy enables the synthesis of valuable δ-chloro-arylsulfonamide and <i>N</i>-arylsulfonylpyrrolidine motifs in moderate yields. This blue LED-induced method utilizes more readily available reagents, providing advantages in terms of cost efficiency, broad substrate scope, and functional-group compatibility.
Authors
- Dianjun Li (ORCID: https://orcid.org/0000-0002-2353-641X)
- Jinhui Yang (ORCID: https://orcid.org/0000-0002-9381-1560)
- Jinkai Hu (ORCID: https://orcid.org/0009-0000-7783-8467)
- Hui Liu
- Chenglei Yang
- Xiaotao Qin
- Ao-Tong Shi
- Qing-Long Lv
Institutions
- Ningxia University (CN)
Publication Details
- Journal
- Organic & Biomolecular Chemistry
- Published
- 2024-12-03
- DOI
- https://doi.org/10.1039/d4ob01484g
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Ningxia Province