Self-criticism predicts antidepressant effects of intermittent theta-burst stimulation in Major Depressive Disorder

Our data suggests that iTBS to the left DLPFC engages a circuit related to self-criticism. Higher levels of self-criticism predicted better response to iTBS with an adjuvant that enhances synaptic plasticity. This suggests that personality traits may be used to tailor non-invasive neurostimulation treatments.

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Publication Details

Journal
Journal of Affective Disorders
Published
2024-12-03
DOI
https://doi.org/10.1016/j.jad.2024.12.006
Citations
2
Primary Topic
Treatment of Major Depression
Type
article
Field-Weighted Citation Impact
0.90
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article

Self-criticism predicts antidepressant effects of intermittent theta-burst stimulation in Major Depressive Disorder

Daniel C. Kopala‐Sibley, Alexander McGirr, Molly Watson, Myren N. Sohn et al.
2 citations
Journal of Affective Disorders
Treatment of Major Depression
0.90
article

Self-criticism predicts antidepressant effects of intermittent theta-burst stimulation in Major Depressive Disorder

Daniel C. Kopala‐Sibley, Alexander McGirr, Molly Watson, Myren N. Sohn, Aliya Jomha
article en
2 citations

Abstract

Our data suggests that iTBS to the left DLPFC engages a circuit related to self-criticism. Higher levels of self-criticism predicted better response to iTBS with an adjuvant that enhances synaptic plasticity. This suggests that personality traits may be used to tailor non-invasive neurostimulation treatments.

Journal of Affective DisordersVol. 372
University of Calgary (CA), Mount Royal University (CA)
Gender equality
Openalex Percentile: Top 22%
Treatment of Major Depression
0.90
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