Analysis of outcomes of penetrating colonic injuries managed with or without fecal diversion

Traumatic colorectal injuries can be managed by either fecal diversion or primary repair / resection and anastomosis. We aimed to study differences in outcomes in adult patients managed with or without fecal diversion at time of initial operation. The National Trauma Databank (NTDB) was used to identify adult patients (ages 18-64 years) with penetrating colonic injuries for the years 2013-2015. We included patients with Injury Severity Score (ISS) of 9-24 excluding patients with concomitant extra-abdominal Abbreviated Injury Scale (AIS) score of 3 or more. Subjects arriving without signs of life, expiring in ER or with missing data were excluded. Data was collected for age, gender, vital signs on presentation, discharge disposition and length of stay (LOS). Patients were divided into two groups based on whether or not fecal diversion was performed within 1 day of presentation. Primary outcome assessed was in-hospital mortality and unplanned return to OR. Secondary outcomes were acute kidney injury (AKI), acute respiratory distress syndrome (ARDS), deep vein thrombosis (DVT), pulmonary embolism (PE), pneumonia, organ surgical site infection (SSI), deep SSI, severe sepsis and unplanned intubation. Statistical analysis was conducted using SPSS for windows. P-value < 0.05 was considered statistically significant. Of 2,598,467 patients, 5344 (0.21%) sustained a penetrating colonic injury. 2339 (43.8%) patients met criteria for age, ISS, AIS, signs of life and ED outcome. 173 patients underwent fecal diversion within 24 h of presentation (Group 1) while 708 did not (Group 2). Patients with missing data were excluded leaving 162 patients in Group 1 and 657 patients in Group 2. Groups 1 and 2 were noted to be similar in terms of ISS (median of 10 in both), age (median of 31 vs 29 years), percentage of male patients (85.2% vs 87.8%; p = 0.44), mean systolic blood pressure (127 mmHg vs 126 mmHg; p = 0.54), mean pulse rate (95.4 vs 94.5; p = 0.60) and mean respiratory rate (20.4 vs 20.1; p = 0.56) respectively. Median LOS was 10 days in both groups. No statistically significant differences were found between groups 1 and 2 in the primary outcomes of in-hospital mortality (2.4% vs 3.5%; OR: 1.43; 95% confidence interval (CI): 0.49-4.20) or unplanned return to OR (4.3% vs 7.8%; OR: 1.86; 95% CI: 0.83-4.19). No statistically significant differences were noted between groups 1 and 2 in the secondary outcomes of AKI (3.7% vs 3.8%; OR: 1.03; 95% CI 0.41-2.55), ARDS (1.2% VS 1.7%; OR: 1.36; 95% CI 0.30-6.21), DVT (1.9% vs 4.0%; OR: 2.18; 95% CI 0.65-7.31), PE (1.9% vs 2.0%; OR: 1.07; 95% CI 0.30-3.80), pneumonia (4.9% vs 5.3%; OR: 1.08; 95% CI 0.49-2.38), organ SSI (3.7% vs 7.0%; OR: 1.96; 95% CI: 0.82-4.67), deep SSI (3.7% vs 4.4%; OR: 1.20, 95% CI 0.49-2.94), severe sepsis (3.7% vs 3.3%; OR: 0.90; 95% CI: 0.36-2.26) or unplanned intubation (1.9% vs 1.7%; OR: 0.90; 95% CI 0.25-3.27). Adult patients with penetrating colonic injuries with ISS 9-24 in the absence of serious extra-abdominal injury who undergo surgery within 24 h of presentation do not seem to derive a statistically significant benefit from fecal diversion in terms of post-operative complications and mortality. In more severely injured patients fecal diversion may continue to provide a benefit.