Multicenter, prospective, single-arm clinical study to investigate the efficacy and safety of Zoladex (Goserelin acetate) 10.8 mg prior to surgery in Chinese premenopausal women with symptomatic uterine fibroids
Goserelin acetate 10.8 mg pretreatment can effectively reduce the volume of uterine fibroids and uterus, lower estrogen levels and improve anemia symptoms. It could also improve the quality of life of patients, showing good safety and tolerance. This pretreatment was effective, safe, and generally well tolerated.
Authors
- Shuzhong Yao
- Yajing Wei
- Jilong Yao
- Keqin Hua
- Mei Ji (ORCID: https://orcid.org/0000-0002-7049-1525)
- Honghui Shi (ORCID: https://orcid.org/0000-0003-3908-1322)
- Hongluan Mao (ORCID: https://orcid.org/0000-0002-3050-4299)
- Youguo Chen (ORCID: https://orcid.org/0000-0003-0510-6720)
- Xinmei Zhang (ORCID: https://orcid.org/0000-0001-6474-3477)
- Yanchun Liang (ORCID: https://orcid.org/0000-0001-7756-1621)
- Qing Yang (ORCID: https://orcid.org/0000-0002-6379-7577)
- Junying Tang (ORCID: https://orcid.org/0000-0002-9768-2233)
- Ruyu Yang
- Biqi Huang
- Guoyun Wang
Institutions
- Sun Yat-sen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Soochow University (CN)
- Shenzhen Maternity and Child Healthcare Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Women's Hospital, School of Medicine, Zhejiang University (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
- First Affiliated Hospital of Soochow University (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- Qilu Hospital of Shandong University (CN)
- Chongqing Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- Gynecological Endocrinology
- Published
- 2024-12-03
- DOI
- https://doi.org/10.1080/09513590.2024.2427190
- Citations
- 1
- Primary Topic
- Uterine Myomas and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.58
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province
- National Key Research and Development Program of China