Predicting Pharmacokinetics of Active Constituents in Spatholobi caulis by Using Physiologically Based Pharmacokinetic Models
The PBPK models of four constituents can be used to predict the pharmacokinetic characteristics in humans after oral administration of SPC and provide useful data for safe and rational medication in clinical practice.
Authors
- Ruihu Du
- You-Bo Zhang (ORCID: https://orcid.org/0000-0003-4650-8654)
- Zheng Yang (ORCID: https://orcid.org/0000-0003-1898-2260)
- Ludi Li
- Xiaoyan Liu (ORCID: https://orcid.org/0000-0002-1732-5923)
- Qi Wang (ORCID: https://orcid.org/0000-0002-2653-3310)
- Tao Zhang (ORCID: https://orcid.org/0000-0002-6261-9074)
- Yingzi Li (ORCID: https://orcid.org/0000-0001-7507-9751)
Institutions
- Peking University (CN)
- State Administration of Traditional Chinese Medicine of the People's Republic of China (CN)
- China National Center for Food Safety Risk Assessment (CN)
Publication Details
- Journal
- Pharmaceuticals
- Published
- 2024-12-03
- DOI
- https://doi.org/10.3390/ph17121621
- Citations
- 1
- Primary Topic
- Plant Toxicity and Pharmacological Properties
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- Natural Science Foundation of Beijing Municipality