Usenamine A: a potential therapeutic agent for rheumatoid arthritis and ankylosing spondylitis through its anti-inflammatory activity
Our findings suggest that UA has potential as a binding target for TNF, suppresses inflammatory cytokines in PBMCs, and exhibits anti-inflammatory effects on arthritis in a mouse model.
Authors
- Seung Cheol Shim (ORCID: https://orcid.org/0000-0002-3199-359X)
- Tae‐Jong Kim (ORCID: https://orcid.org/0000-0002-2871-1635)
- Moon‐Ju Kim (ORCID: https://orcid.org/0000-0002-8018-6903)
- Hyun Hee Jang (ORCID: https://orcid.org/0000-0002-0358-8247)
- Eun Jeong Won (ORCID: https://orcid.org/0000-0002-8750-4257)
- Kandasamy Saravanakumar (ORCID: https://orcid.org/0000-0002-4465-4378)
- Zijun Li (ORCID: https://orcid.org/0000-0001-5049-7244)
- Namki Cho (ORCID: https://orcid.org/0000-0002-9936-3463)
- Yu Jeong Lee (ORCID: https://orcid.org/0000-0003-1282-4210)
Institutions
- Chonnam National University (KR)
- Ulsan College (KR)
- Asan Medical Center (KR)
- University of Ulsan (KR)
- Chonnam National University Hospital (KR)
- Chungnam National University Hospital (KR)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-12-03
- DOI
- https://doi.org/10.3389/fphar.2024.1456216
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea