FTO-mediated demethylation of MTUS1/ATIP1 promotes tumor progression in head and neck squamous cell carcinoma
Our research elucidated the functional importance of FTO-mediated m<sup>6</sup>A demethylation of MTUS1/ATIP1, suggesting that targeting the FTO-MTUS1/ATIP1 axis could be a prospective novel approach for treating HNSCC.
Authors
- Dongxiao Tang (ORCID: https://orcid.org/0000-0003-2462-0338)
- Wuguo Li (ORCID: https://orcid.org/0000-0001-6765-5368)
- Congyuan Cao (ORCID: https://orcid.org/0009-0005-6300-3166)
- Anxun Wang (ORCID: https://orcid.org/0000-0002-8498-6609)
Institutions
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-12-03
- DOI
- https://doi.org/10.1186/s12885-024-13253-y
- Citations
- 3
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- National Natural Science Foundation of China