Resistant and refractory migraine – two different entities with different comorbidities? Results from the REFINE study
REFINE data indicate that individuals with ResM and RefM have a higher burden of comorbidities than those with NRNRM. It can be postulated that those comorbidities may have an impact on the progression of migraine from a form that is easy to treat to a form that is resistant or refractory to treatments. Longitudinal studies are needed to understand the direction of the association between ResM or RefM and those comorbidities and if proper treatment of comorbidities might help overcome treatment resistance or refractoriness.
Authors
- Paolo Martelletti (ORCID: https://orcid.org/0000-0002-6556-4128)
- Martina Gentile
- William Wells-Gatnik (ORCID: https://orcid.org/0009-0002-5564-2783)
- Loukia Apostolakopoulou (ORCID: https://orcid.org/0000-0001-7995-2124)
- Isabel Pavão Martins (ORCID: https://orcid.org/0000-0002-9611-7400)
- Ghaemeh Nabaei
- Christian Lampl (ORCID: https://orcid.org/0000-0003-1756-1181)
- Jurgita Vainauskienė
- Jakob Paungarttner
- Carine Rosignoli (ORCID: https://orcid.org/0000-0001-5036-2382)
- Mark Braschinsky (ORCID: https://orcid.org/0000-0002-3457-0242)
- Patricia Pozo‐Rosich (ORCID: https://orcid.org/0000-0003-0796-4702)
- Margarita Sánchez del Río (ORCID: https://orcid.org/0000-0001-7724-2890)
- Giancarla Iaccarino (ORCID: https://orcid.org/0000-0001-7654-2672)
- Zaza Katsarava (ORCID: https://orcid.org/0000-0002-9932-1159)
- Kristina Ryliškienė (ORCID: https://orcid.org/0000-0001-9596-1733)
- Simona Sacco (ORCID: https://orcid.org/0000-0003-0651-1939)
- Valeria Caponnetto (ORCID: https://orcid.org/0000-0003-4573-6110)
- Albert Muñoz‐Vendrell (ORCID: https://orcid.org/0000-0001-8221-865X)
- Raquel Gil‐Gouveia (ORCID: https://orcid.org/0000-0002-4256-4256)
- Marta Waliszewska‐Prosół (ORCID: https://orcid.org/0000-0002-9074-2803)
- Aynur Özge (ORCID: https://orcid.org/0000-0003-2797-2398)
- Raffaele Ornello (ORCID: https://orcid.org/0000-0001-9501-4031)
- Agnese Onofri (ORCID: https://orcid.org/0000-0002-9697-0970)
- Sławomir Budrewićz (ORCID: https://orcid.org/0000-0002-2044-6347)
- Fabrizio Vernieri (ORCID: https://orcid.org/0000-0002-9594-9336)
- Maria Pia Prudenzano (ORCID: https://orcid.org/0000-0001-9259-8158)
- M. Carnovali
- Dimos D. Mitsikostas (ORCID: https://orcid.org/0000-0002-4691-3388)
- Dilan Bayar Narin
- S. Avaltroni
- Olga Sved
Institutions
- University of Lisbon (PT)
- Università Campus Bio-Medico (IT)
- Vilnius University (LT)
- National and Kapodistrian University of Athens (GR)
- University of L'Aquila (IT)
- Wroclaw Medical University (PL)
- Shariati Hospital (IR)
- Vall d'Hebron Hospital Universitari (ES)
- Hospital da Luz (PT)
- Clinica Universidad de Navarra (ES)
- Eginition Hospital (GR)
- Mersin Üniversitesi (TR)
- University of Tartu (EE)
- University of Duisburg-Essen (DE)
- Tehran University of Medical Sciences (IR)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- The Journal of Headache and Pain
- Published
- 2024-12-03
- DOI
- https://doi.org/10.1186/s10194-024-01910-3
- Citations
- 9
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 3.47