Phytochemical screening and <i>in vitro</i> antibacterial activity of <i>Echinops kebericho</i> Mesfin tuber extracts: experimental studies

The percentage yield of the plant extracts ranged from 6.25% to 7.85%. The methanol extract of <i>Echinops kebericho</i> Mesfin had the highest inhibitory effect on <i>S. aureus</i> (ATCC 25923) (16.67 ± 0.58 mm), followed by <i>E. coli</i> (ATCC 25922) (11.0 ± 1.73 mm). Phytochemical screening of leaves from the methanol and petroleum ether extracts of the plant revealed the presence of phytochemicals such as alkaloids, flavonoids, tannins, and cardiac glycosides. The present study revealed that the extracts of these plants have antibacterial activity. However, researchers should conduct further studies on the safety margin and quantitative bioactive isolation of selected medicinal plants.