Direct minimization of normal‐tissue toxicity via an NTCP‐based IMPT planning method
NTCP-IMPT effectively minimizes normal-tissue toxicity and improves the sparing of OARs associated with side effects while maintaining comparable tumor coverage compared to standard IMPT.
Authors
- Wangyao Li (ORCID: https://orcid.org/0000-0001-9312-4931)
- Bin Qin (ORCID: https://orcid.org/0000-0001-5082-7805)
- Xu Liu (ORCID: https://orcid.org/0000-0002-9067-3393)
- Jiaxin Li (ORCID: https://orcid.org/0000-0001-5360-0219)
- Wei Wang (ORCID: https://orcid.org/0000-0002-0284-8414)
- Hao Gao (ORCID: https://orcid.org/0000-0003-1064-2149)
- Yuting Lin (ORCID: https://orcid.org/0000-0001-6227-8321)
Institutions
- Chinese Academy of Sciences (CN)
- University of Kansas Medical Center (US)
- Institute of Modern Physics (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Medical Physics
- Published
- 2024-12-03
- DOI
- https://doi.org/10.1002/mp.17559
- Citations
- 2
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- National Natural Science Foundation of China
- National Institutes of Health