Retrospective Study on Short-Term Reverse Cardiac Remodeling in Obese Patients Undergoing Sleeve Gastrectomy

Severe obesity is closely associated with an increased risk of comorbidities and alterations in cardiac structure and function. The primary objective of this study was to investigate cardiovascular (CV) risk factors and ventricular remodeling in individuals from an obese population eligible for bariatric surgery. The secondary objective was to evaluate changes in anthropometric, clinical laboratory, and echocardiographic measurements 12 weeks after surgery compared to baseline values. This retrospective observational cohort study involved patients from a single specialized bariatric surgery center. A total of 35 patients were included (mean age 41.5 ± 10.3 years; BMI 43.4 ± 6.6 kg/m<sup>2</sup>), of whom 34.2% had a family history of coronary artery disease (CAD), 5.7% had a prior history of CAD, 8 had essential hypertension, 11.4% had dyslipidemia, 20% were smokers, and 8.6% were former smokers. Approximately 57% of the patients exhibited concentric left ventricular remodeling, and 14% had grade I diastolic dysfunction. At 12 weeks post-surgery, with an average weight loss of 25 kg and a mean BMI reduction of 8.5 kg/m<sup>2</sup>, 14% of the patients still exhibited concentric left ventricular remodeling, and about 11% had grade I diastolic dysfunction. Bariatric surgery contributes to the improvement of cardiac function and structure over time as a result of significant weight loss.

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Journal
Journal of Cardiovascular Development and Disease
Published
2024-12-03
DOI
https://doi.org/10.3390/jcdd11120389
Citations
2
Primary Topic
Cardiovascular Function and Risk Factors
Type
article
Field-Weighted Citation Impact
0.80
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article

Retrospective Study on Short-Term Reverse Cardiac Remodeling in Obese Patients Undergoing Sleeve Gastrectomy

Paola Di Pietro, Michele Ciccarelli, Carmine Izzo, Valeria Visco et al.
2 citations
Journal of Cardiovascular Development and Disease
Cardiovascular Function and Risk Factors
0.80
article

Retrospective Study on Short-Term Reverse Cardiac Remodeling in Obese Patients Undergoing Sleeve Gastrectomy

Paola Di Pietro, Michele Ciccarelli, Carmine Izzo, Valeria Visco, Davide Bonadies, Nicola Virtuoso, Maria Rosaria Rusciano, Giuseppe Caliendo, Alessia Bramanti, Albino Carrizzo, Francesco Loria, Alessandra Cirillo, Eleonora Venturini, Luigi Schiavo, Carmine Vecchione, Vincenzo Pilone
article en
2 citations

Abstract

Severe obesity is closely associated with an increased risk of comorbidities and alterations in cardiac structure and function. The primary objective of this study was to investigate cardiovascular (CV) risk factors and ventricular remodeling in individuals from an obese population eligible for bariatric surgery. The secondary objective was to evaluate changes in anthropometric, clinical laboratory, and echocardiographic measurements 12 weeks after surgery compared to baseline values. This retrospective observational cohort study involved patients from a single specialized bariatric surgery center. A total of 35 patients were included (mean age 41.5 ± 10.3 years; BMI 43.4 ± 6.6 kg/m<sup>2</sup>), of whom 34.2% had a family history of coronary artery disease (CAD), 5.7% had a prior history of CAD, 8 had essential hypertension, 11.4% had dyslipidemia, 20% were smokers, and 8.6% were former smokers. Approximately 57% of the patients exhibited concentric left ventricular remodeling, and 14% had grade I diastolic dysfunction. At 12 weeks post-surgery, with an average weight loss of 25 kg and a mean BMI reduction of 8.5 kg/m<sup>2</sup>, 14% of the patients still exhibited concentric left ventricular remodeling, and about 11% had grade I diastolic dysfunction. Bariatric surgery contributes to the improvement of cardiac function and structure over time as a result of significant weight loss.

Journal of Cardiovascular Development and DiseaseVol. 11(12)
University of Salerno (IT), Istituto Neurologico Mediterraneo (IT), Federico II University Hospital (IT), Ospedali Riuniti San Giovanni di Dio e Ruggi d'Aragona (IT)
Good health and well-being
Openalex Percentile: Top 22%
Cardiovascular Function and Risk Factors
0.80
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