Culcinoside E, a new sulfated steroidal biglycoside from the starfish <i>Culcita novaeguineae</i>
Using various chromatographic separations, six steroid glycoside derivatives, including one new compound named culcinoside E (<b>1</b>), were isolated from the methanol extract of the starfish <i>Culcita novaeguineae</i>. Their structures were confirmed by detailed analysis of the 1D, 2D NMR, and HR ESI QTOF mass spectra. Among isolated compounds, culcinoside E (<b>1</b>), diplasterioside A (<b>5</b>), and thornasteroside A (<b>6</b>) inhibited growth of <i>Enterococcus faecalis</i>, whereas culcitoside C<sub>1</sub> (<b>3</b>) was active on <i>Candida albicans</i>.
Authors
- Đào Việt Hà
- Trần Thị Hồng Hạnh
- Nguyễn Xuân Cường (ORCID: https://orcid.org/0000-0003-1855-6181)
- Trần Hồng Quang (ORCID: https://orcid.org/0000-0003-1387-5271)
- Le Thi Vien
- Nguyen Dang Ngai
Institutions
- Institute of Marine Geology and Geophysics (VN)
- Institute of Oceanography
- Vietnam Academy of Science and Technology (VN)
Publication Details
- Journal
- Journal of Asian Natural Products Research
- Published
- 2024-12-03
- DOI
- https://doi.org/10.1080/10286020.2024.2434564
- Citations
- 2
- Primary Topic
- Marine Sponges and Natural Products
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- Vietnam Academy of Science and Technology