Exosomes derived from minor salivary gland mesenchymal stem cells: a promising novel exosome exhibiting pro-angiogenic and wound healing effects similar to those of adipose-derived stem cell exosomes
Our study confirms that MSGMSC-exos exhibit highly similar wound healing and angiogenesis-promoting functions compared to ADSC-exos, and the proteins involved in promoting wound healing in both are relatively conserved. Moreover, MSGMSC-exos show stronger anti-scar formation and anti-inflammatory effects than ADSC-exos. This suggests that MSGMSCs are a promising stem cell source with broad applications in wound healing treatment.
Authors
- Yimou Sun (ORCID: https://orcid.org/0000-0002-6882-5100)
- Enhang Lu (ORCID: https://orcid.org/0000-0001-5782-9328)
- Haibo Xiang (ORCID: https://orcid.org/0000-0002-2780-2949)
- Zhixuan Sun (ORCID: https://orcid.org/0009-0004-6482-8808)
- Zhenkun Zhao
- Pengbing Ding (ORCID: https://orcid.org/0000-0003-0122-9029)
- Jiaying Qian
- Zhenmin Zhao (ORCID: https://orcid.org/0000-0002-7177-2169)
- Se-Yeon Lee (ORCID: https://orcid.org/0000-0003-4648-228X)
Institutions
- Seoul National University (KR)
- Peking University (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2024-12-03
- DOI
- https://doi.org/10.1186/s13287-024-04069-5
- Citations
- 13
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- National Natural Science Foundation of China