Impact of the Number of Administered Systemic Treatment Lines on Local Response to Radiation Therapy for Multiple Myeloma

In this large retrospective cohort of MM patients, the number of systemic treatment lines administered before RT had no impact on the local response, confuting concerns of cross-resistance raised by multiple preclinical studies. Disease control after RT was optimal, and instances of severe toxicities during treatment were rare.

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Publication Details

Journal
Advances in Radiation Oncology
Published
2024-12-03
DOI
https://doi.org/10.1016/j.adro.2024.101696
Citations
1
Primary Topic
Multiple Myeloma Research and Treatments
Type
article
Field-Weighted Citation Impact
0.45
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article

Impact of the Number of Administered Systemic Treatment Lines on Local Response to Radiation Therapy for Multiple Myeloma

Michela Buglione, Stefania Nici, Paolo Borghetti, Luigi Spiazzi et al.
1 citations
Advances in Radiation Oncology
Multiple Myeloma Research and Treatments
0.45
article

Impact of the Number of Administered Systemic Treatment Lines on Local Response to Radiation Therapy for Multiple Myeloma

Michela Buglione, Stefania Nici, Paolo Borghetti, Luigi Spiazzi, Eneida Mataj, Luca Triggiani, Ludovica Pegurri, Andrea Emanuele Guerini, Stefano Maria Magrini, Giorgio Facheris, Angelo Belotti, Alessandra Tucci, Marco Lorenzo Bonù, S. Riga
article en
1 citations

Abstract

In this large retrospective cohort of MM patients, the number of systemic treatment lines administered before RT had no impact on the local response, confuting concerns of cross-resistance raised by multiple preclinical studies. Disease control after RT was optimal, and instances of severe toxicities during treatment were rare.

Advances in Radiation OncologyVol. 10(3)
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT), University of Brescia (IT)
Good health and well-being
Openalex Percentile: Top 30%
Multiple Myeloma Research and Treatments
0.45
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