Quinuclidine‐Catalyzed Electrochemical Minisci Acylation of <i>N</i>‐Heteroarenes with Acylhydrazines
Abstract The quinuclidine (Qu)‐catalyzed activation of acylhydrazines to afford the corresponding acyl radicals remains an unmet challenge. To address this challenge, we report a synergistic strategy by combining electro‐oxidation with Qu‐based HAT catalysis. Enabled by this strategy, the electrochemical Minisci acylation of N ‐heterocycles with acylhydrazines was realized for the first time.
Authors
- Kun Xu (ORCID: https://orcid.org/0000-0002-0419-8822)
- Cheng‐Chu Zeng (ORCID: https://orcid.org/0000-0002-5659-291X)
- Dehui Wang (ORCID: https://orcid.org/0000-0002-9185-9034)
- Haonan Zhang (ORCID: https://orcid.org/0000-0002-9467-2566)
Institutions
- Beijing University of Technology (CN)
- Beijing University of Chemical Technology (CN)
- University of Science and Technology Beijing (CN)
Publication Details
- Journal
- ChemCatChem
- Published
- 2024-12-03
- DOI
- https://doi.org/10.1002/cctc.202401642
- Citations
- 2
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.50
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Beijing Municipality