Efficacy of colistin-based combinations against pandrug-resistant whole-genome-sequenced Klebsiella pneumoniae isolated from hospitalized patients in Egypt: an in vitro/vivo comparative study
This study represents the first comparative in vitro and in vivo investigation of the efficacy of colistin + doxycycline and colistin + levofloxacin combinations in clinical PDR ColRKp isolates characterized at a genomic level.
Authors
- Nelly M. Mohamed (ORCID: https://orcid.org/0000-0001-9073-5032)
- Rhiannon Evans (ORCID: https://orcid.org/0000-0002-8510-0988)
- Azza S. Zakaria (ORCID: https://orcid.org/0000-0003-3772-1381)
- Amal M Khalil (ORCID: https://orcid.org/0009-0002-9842-5826)
- Eriny T. Attalla (ORCID: https://orcid.org/0009-0008-4721-9647)
- Nesrin S. Tolba
Institutions
- Quadram Institute (GB)
- Alexandria University (EG)
Publication Details
- Journal
- Gut Pathogens
- Published
- 2024-12-03
- DOI
- https://doi.org/10.1186/s13099-024-00667-z
- Citations
- 1
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.17
Funders
- Science and Technology Development Fund
- Alexandria University