The impact of 3D real-IR delayed post gadolinium MRI parameterisation on the diagnostic performance and optimal descriptor selection in Ménière’s disease
Question Delayed post-gadolinium ZPE (FLAIR) and NSE (REAL-IR) sequences are widely applied for diagnosing MD, but their relative benefits remain unclear. Findings Optimised NSE sequences improve perilymphatic depiction and influence the selection of the optimal MRI descriptors, but do not improve diagnostic performance. Clinical relevance Radiologists may continue to apply either ZPE or NSE sequences since they offer similar diagnostic abilities, but the choice of the sequence will influence which MRI features should be evaluated to support the diagnosis of MD.
Authors
- Philip Touska (ORCID: https://orcid.org/0000-0002-9350-0420)
- Irumee Pai (ORCID: https://orcid.org/0000-0003-3023-4572)
- Steve Connor (ORCID: https://orcid.org/0000-0001-5502-4972)
- Sébastien Ourselin (ORCID: https://orcid.org/0000-0002-5694-5340)
- Joseph V. Hajnal (ORCID: https://orcid.org/0000-0002-2690-5495)
- David E. Price
Institutions
- Guy's Hospital (GB)
- St Thomas' Hospital (GB)
- King's College London (GB)
- King's College School (GB)
- King's College Hospital (GB)
Publication Details
- Journal
- European Radiology
- Published
- 2024-12-03
- DOI
- https://doi.org/10.1007/s00330-024-11218-0
- Citations
- 3
- Primary Topic
- Vestibular and auditory disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.74
Funders
- NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research
- Cancer Research UK
- National Institute for Health and Care Research
- King's College London
- Engineering and Physical Sciences Research Council
- Centre For Medical Engineering, King’s College London