Direct oral provocation test with beta-lactams in Brazilian children and adolescents

>90 % of the sample was delabeled as allergic to BL. There were no severe reactions, confirming the safety of direct OPT in this age group. Among the reactors, 3 patients presented symptoms on the first day of testing before receiving the second dose and one had symptoms on 5 days, indicating that further studies are needed on the optimal duration of the OPT.

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Publication Details

Journal
Jornal de Pediatria
Published
2024-12-03
DOI
https://doi.org/10.1016/j.jped.2024.11.003
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
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article

Direct oral provocation test with beta-lactams in Brazilian children and adolescents

Fábio Chigres Kuschnir, Maria Inês Perelló, Mara Morelo Rocha Félix, Nathalia Mota Gomes Almeida
Jornal de Pediatria
Drug-Induced Adverse Reactions
article

Direct oral provocation test with beta-lactams in Brazilian children and adolescents

Fábio Chigres Kuschnir, Maria Inês Perelló, Mara Morelo Rocha Félix, Nathalia Mota Gomes Almeida
article en

Abstract

>90 % of the sample was delabeled as allergic to BL. There were no severe reactions, confirming the safety of direct OPT in this age group. Among the reactors, 3 patients presented symptoms on the first day of testing before receiving the second dose and one had symptoms on 5 days, indicating that further studies are needed on the optimal duration of the OPT.

Jornal de PediatriaVol. 101(3)
Universidade do Estado do Rio de Janeiro (BR), Hospital Universitário Pedro Ernesto (BR), Universidade Federal do Estado do Rio de Janeiro (BR)
Zero hunger
Openalex Percentile: Top 78%
Drug-Induced Adverse Reactions
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