Integrative Analysis Identifies NSUN2 as an Essential Coordinator for Glioma Malignancy and Glucose Metabolism
Our findings highlight NSUN2 as a critical regulator of glioma malignancy. Targeting NSUN2 disrupts key pathways in glioma progression, suggesting it as a promising therapeutic target. Our work underscores the potential of NSUN2 inhibition to enhance treatment efficacy and improve patient outcomes in glioma.
Authors
- Mina Chen (ORCID: https://orcid.org/0000-0002-7446-3978)
- Linzi Ji
- Wanchun Yang (ORCID: https://orcid.org/0000-0003-4852-1887)
- Yongjun Shu (ORCID: https://orcid.org/0000-0003-4463-0218)
- Zhihao Wang (ORCID: https://orcid.org/0000-0003-1561-4040)
- Shuxin Zhang (ORCID: https://orcid.org/0000-0003-4715-9070)
- Yan‐Hui Liu (ORCID: https://orcid.org/0000-0002-3722-3334)
- Yunbo Yuan
- Yuze He
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- State Key Laboratory of Biotherapy
Publication Details
- Journal
- The Journal of Gene Medicine
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/jgm.70004
- Citations
- 3
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- National Natural Science Foundation of China