Spatial omics-based machine learning algorithms for the early detection of hepatocellular carcinoma
In conclusion, we present the development and application of a new biomarker platform, which can identify effective biomarkers for the early detection of HCC. This platform may also apply to other diseases, in which changes in N-linked glycosylation are known to occur.
Authors
- Alyson Black (ORCID: https://orcid.org/0000-0002-1847-4197)
- Andrew T. DelaCourt (ORCID: https://orcid.org/0000-0003-0280-1445)
- Yujin Hoshida (ORCID: https://orcid.org/0000-0001-9430-1426)
- Naoto Kubota (ORCID: https://orcid.org/0000-0002-1849-5078)
- Lisa Quirk (ORCID: https://orcid.org/0000-0001-8959-3815)
- Amit G. Singal (ORCID: https://orcid.org/0000-0002-1172-3971)
- Anand S. Mehta (ORCID: https://orcid.org/0000-0002-9846-9389)
- Mengjun Wang (ORCID: https://orcid.org/0000-0003-3001-3569)
- David Lewin (ORCID: https://orcid.org/0000-0002-0531-6018)
- Calvin R.K. Blaschke (ORCID: https://orcid.org/0000-0003-3988-6817)
- G. David Huffman
- Shaaron Ochoa-Rios (ORCID: https://orcid.org/0000-0002-0091-2355)
- Peggi M. Angel (ORCID: https://orcid.org/0000-0002-4436-555X)
- Stéphane Elie Grauzam (ORCID: https://orcid.org/0000-0001-7524-258X)
- Jennifer R. Bethard (ORCID: https://orcid.org/0000-0001-7653-156X)
- Lauren Ball (ORCID: https://orcid.org/0000-0002-5394-0931)
- Richard R. Drake (ORCID: https://orcid.org/0000-0002-6285-6440)
- Danielle A. Scott (ORCID: https://orcid.org/0000-0003-2461-9812)
- James W. Dressman (ORCID: https://orcid.org/0000-0002-6659-6367)
- Stephen Castellino (ORCID: https://orcid.org/0000-0001-9538-7057)
- Yuko Kono (ORCID: https://orcid.org/0000-0002-9357-4104)
- Purva Gopal (ORCID: https://orcid.org/0000-0001-7125-695X)
- Adam C. Yopp (ORCID: https://orcid.org/0000-0002-5887-5315)
- Hongyan Liang (ORCID: https://orcid.org/0000-0002-1999-0097)
- Muhammed Bayram (ORCID: https://orcid.org/0000-0002-2054-342X)
Institutions
- Medical University of South Carolina (US)
- University of California San Diego (US)
- SignPath Pharma (United States) (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Communications Medicine
- Published
- 2024-12-03
- DOI
- https://doi.org/10.1038/s43856-024-00677-7
- Citations
- 5
- Primary Topic
- Glycosylation and Glycoproteins Research
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- Division of Cancer Prevention, National Cancer Institute
- National Cancer Institute