Somatostatin Receptor Imaging in the Diagnosis and Management of Parathyroid Neuroendocrine Neoplasia
PET/CT with [68Ga]-DOTA-peptides can detect parathyroid NENs. The incidental detection of high [68Ga]-DOTA-peptide uptake in the parathyroid region during whole-body PET/CT may prompt biochemical evaluation for PHPT. We suggest that endothelial SST expression mediates high radiopharmaceutical uptake by PAs and that SSA treatment can reduce hypercalcemia in PHPT patients.
Authors
- Elena Grineva (ORCID: https://orcid.org/0000-0003-0042-7680)
- Karina Pogosian (ORCID: https://orcid.org/0000-0003-0628-0085)
- Pavel Ryazanov (ORCID: https://orcid.org/0000-0003-3684-8612)
- Polina Sokolnikova (ORCID: https://orcid.org/0000-0001-7833-7840)
- Т. Л. Каронова (ORCID: https://orcid.org/0000-0002-1547-0123)
- Д. В. Рыжкова (ORCID: https://orcid.org/0000-0002-7086-9153)
- Irina Matsueva (ORCID: https://orcid.org/0000-0003-2996-0067)
- Uliana Tsoy
- М. А. Салов (ORCID: https://orcid.org/0000-0002-9530-3447)
- K. Yakovenko
- Olga Yudina (ORCID: https://orcid.org/0000-0002-2105-5153)
Institutions
- Federal Almazov North-West Medical Research Centre (RU)
Publication Details
- Journal
- Diagnostics
- Published
- 2024-12-03
- DOI
- https://doi.org/10.3390/diagnostics14232718
- Primary Topic
- Neuroendocrine Tumor Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 0.00