Training Status Influences Regulation of Muscle and PBMC TLR4 Expression and Systemic Cytokine Responses to Vigorous Endurance Exercise
These findings highlight the potential of endurance training to mitigate TLR4-mediated signaling, such as systemic inflammation, and shed light on the effects of exercise on TLR4 expression in PBMCs and skeletal muscle.
Authors
- Jonathan W. Specht
- Christine M. Mermier (ORCID: https://orcid.org/0000-0001-8779-1885)
- Alyssa R. Bailly (ORCID: https://orcid.org/0000-0002-1800-3969)
- Zachary J. Fennel (ORCID: https://orcid.org/0000-0001-9482-7815)
- Orlando Laitano (ORCID: https://orcid.org/0000-0003-2768-1427)
- Michael R. Deyhle (ORCID: https://orcid.org/0000-0001-8526-4758)
- Jeremy B. Ducharme (ORCID: https://orcid.org/0000-0003-1653-8721)
- Roberto C. Nava (ORCID: https://orcid.org/0000-0003-4538-7539)
Institutions
- New Mexico Department of Health (US)
- University of New Mexico (US)
- University of Utah (US)
- University of Florida (US)
- Center for Health, Exercise and Sport Sciences (RS)
- Mammoth Biosciences (United States) (US)
Publication Details
- Journal
- Medicine & Science in Sports & Exercise
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1249/mss.0000000000003618
- Citations
- 2
- Primary Topic
- Exercise and Physiological Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.50