The Action of Testosterone in Anti-aging, Rejuvenation, and Longevity

Testosterone is an anabolic androgenic steroid hormone, that is, it is a lipid synthesized from cholesterol-steroid, produced by glands and with regulatory action on cellular physiology hormone, whose main actions are to promote masculinization -androgenic effect- and the synthesis of complex molecules from simpler molecules anabolic effect. Our body's three main steroid substances are androgens, estrogens, and corticosteroids. This literature review aims to verify testosterone's action on rejuvenation, anti-aging, and longevity. The integrative literature review is a method that aims to synthesize results obtained in research on a topic or issue, in a systematic, ordered, and comprehensive way. It is called integrative because it provides broader information on a subject/problem, thus constituting a body of knowledge. To carry out the study, a search for scientific articles was carried out through the Virtual Health Library (SCIELO), Latin American and Caribbean Literature in Health Sciences (LILACS), US National Library of Medicine National Center for Biotechnology Information (PUBMED), Social Network for Scientists (ResearchGate) and Virtual Social Network for Academics (Academia.edu) using the terminologies registered in the health sciences descriptors: Anti-aging, hormones, longevity, rejuvenation, and testosterone.